The Hippo signaling pathway is a highly conserved pathway involved in tissue development and regeneration that controls organ size through the regulation of cell proliferation and apoptosis.The core Hippo pathway is composed of a block of kinases, MST1/2 (Mammalian STE20-like protein kinase 1/2) and LATS1/2 (Large tumor suppressor 1/2), which inhib
Failure of loose gully deposits under the effect of rainfall contributes to the potential risk of debris flow.In the past decades, researches on hydraulic mechanism and time-dependent characteristics of loose deposits failure are frequently reported, however adequate measures for reducing debris flow are not available practically.In this context, a
The RNase III enzyme DICER generates both microRNAs (miRNAs) and endogenous short interfering RNAs (endo-siRNAs).Both small RNA species silence gene expression post-transcriptionally in association with the ARGONAUTE (AGO) family of proteins.In mammals, there are four AGO proteins (AGO1-4), of which only AGO2 possesses endonucleolytic activity.siRN
Any organism faces sensory and cognitive limitations which may result in maladaptive decisions.Such limitations are prominent in the context of groups where the relevant information at the individual level may not coincide with collective requirements.Here, we study the navigational decisions exhibited by Paratrechina longicornis ants as they coope
Abstract Background Lymnaeid snails of the genus Austropeplea are an important vector of the liver fluke (Fasciola hepatica), contributing to livestock here production losses in Australia and New Zealand.However, the species status within Austropeplea is ambiguous due to heavy reliance on morphological analysis and a relative lack of genetic data.T